MTB Group Seminar Series: Time-Dependent Vaccine Efficacy Estimation Quantified by a Mathematical Model

Abstract

A vaccination trial consists in choosing a voluntary cohort of susceptible individuals who receive either a vaccine or a placebo shot. This is normally done in the middle of an outbreak of a disease to which the vaccine is supposed to prevent. When the incidence of the infection is constant in time, calculation of vaccine efficacy is straightforward. When the incidence is time-dependent, however, some refinements are necessary and this is purpose of this present model.

Link to the session: https://us06web.zoom.us/j/84215900575?pwd=b0pKVlhvU3Z4WExUa3JPZld0b0NQdz09